Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a dihydroxybenzoic acid derivative used as a flavoring agent. So the oil mimics the antioxidant functions of the berry. Oriental Pharmacy and Experimental Medicine. In addition, methylation of the SOCS3 gene was detected in epithelial cells from UC-CRC biopsy specimens. Application of aronia berry powder inhibited CLDN1 and also increased expression of zonula ocludens-1 (ZO-1) after 12 h. In summary, aronia berry, but not its microbiota-derived catabolites improved intestinal barrier function in a cellular model of chronic colonic inflammation. Oleic acid in the acai berry oil is one of the best natural moisturizers on the planet. lfasalazine (150 mg/kg) were used as positive controls. Local administration of p65 antisense phosphorothioate oligonucleotides abrogated clinical and histological signs of colitis and was more effective in treating TNBS-induced colitis than single or daily administration of glucocorticoids. Amaranth is classified as a pseudocereal, meaning that it’s not technically a cereal grain like wheat or oats, but it shares a comparable set of nutrients and is used in similar ways. Acai Berry (Image:Shutterstock) Additionally, we observed that CO reduced the activation of transcription nuclear factor-κB p65 in DSS-treated colon tissues. Mice that developed acute colitis showed signs of diarrhea, gross rectal bleeding, and weight loss within 6–10 days after ingesting 3%–10% dextran sulfate sodium. [3]  Material Safety Data Sheet. Moreover, by the analysis of Chinese medicines’ category based on their traditional functions, we conclude the category of dampness-drying and detoxificating medicine targeting NF-κB pathway accounts for primary status for amelioration of UC. At present, the uses of acai oil have not been explored to the extent that they should have been. & Nakaya, R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Amaranth is a good source of health-promoting antioxidants. body weight loss, shortened colon length, and increased disease activity index. For those with celiac disease, eating gluten triggers an immune response in the body, causing damage and inflammation in the digestive tract (20). This article takes a close look at grains and their health effects, both the good stuff and the…. The applicability of acai berry oil to reduce acne is vague because its comedogenicity is not yet established. ; Na, H.J. In chronic active ulcerative colitis, infliximab and adalimumab can be used in the case of treatment with immunosuppressive therapy fails and if surgery is not preferred. The health benefits of vanilla stem from vanillin, a major compound in the essence of specific orchid plants. It’s also rich in iron, which helps your body produce blood (5, 6). Add amaranth to smoothies to boost the fiber and protein content, Use it in dishes in place of pasta, rice or couscous, Mix it into soups or stews to add thickness, Make it into a breakfast cereal by stirring in fruit, nuts or cinnamon. In one test-tube study, amaranth was found to reduce several markers of inflammation (13). Although amaranth has only recently gained popularity as a health food, this ancient grain has been a dietary staple in certain parts of the world for millennia. The protein expression of IL6, p-STAT3 and SOCS3 was determined immunohistochemically. UC is a chronic non-specific inflammatory bowel disease, and until now, therapeutic agents for UC including aminosalicylates, corticosteroids and immune inhibitors still cannot exert satisfied effects on patients. L.E.M. Itoh, A.; Isoda, K.; Kondoh, M.; Kawase, M.; Kobayashi, M.; Tamesada, M.; Yagi, K. ic acid on concanavalin a-induced liver injury, Okayasu, I.; Hatakeyama, S.; Yamada, M.; Ohkusa, T.; Inagaki, Y.; Nakaya, R. A novel m. ute and chronic ulcerative colitis in mice. However, chronic inflammation can contribute to chronic disease and has been associated with conditions like cancer, diabetes and autoimmune disorders (12). Oleic acid is a MUFA (monounsaturated fatty acid) and is commonly found in most seed oils. The genotoxicity of the contemplated plant was tried by the single-cell gel electrophoresis comet measure. Additionally, a study in chickens reported that a diet containing amaranth decreased total cholesterol by up to 30% and “bad” LDL cholesterol by up to 70% (16). Appraisal of cytotoxicity of eatable fruits was assessed by MTT measure. Here are a few easy ways to enjoy this nutritious grain: Amaranth is a nutritious, gluten-free grain that provides plenty of fiber, protein and micronutrients. Keywords: Ulcerative colitis, TCM therapy, Experimental research, Pathology, Ultrastructure, Apoptosis Total sugar in Umsellah (51.37 g of glucose equivalent / 100 g of dates) was found higher compared to Khalas (44.78 g of glucose equivalent / 100 g of dates). Sato, K.; Ohkura, S.; Kitahara, Y.; Ohama, T.; of CPI-17 downregula in the dysmotility of the, Neurath, M.F. Small amounts of acai oil can be used as topical application directly to places that show early signs of ageing, like the under eye bags and dark circles, wrinkles at the sides of the eyes and near the jawline to make it firm and elastic. It is to note that acai oil has an ORAC of 21.5 per gram, which means if you have a kg of oil, its ORAC is 21.5 times 1000 which equals 21500. Brown and white rice come from the same grain, but the two types have very different nutrient profiles and health effects. Low fat frozen yoghurt containing CPS exhibited significantly higher specific gravity, weight per gallon, melting resistance, apparent viscosity, total phenol contents and antioxidant scavenging activity in parallel with the increase of the added CPS. for its suppressive effect on concanavalin A (ConA)-induced liver injury in mice. In recent years, Chinese medicines suggest the advantages of alleviating symptoms and signs, decreasing side-effects and recurrence, whose one of mechanisms is related to regulation of NF-κB pathway. Source : [4]  After 12 h of IC treatment, Caco-2 cells had increased claudin 1 (CLDN1) relative to the untreated control. Antioxidants are naturally occurring compounds that help protect against harmful free radicals in the body. They collect the berries, ground them to obtain juice and after drinking it, they cause themselves to vomit. colitis. are hepatoprotective through their suppression of immune-mediated liver inflammation. One study in hamsters showed that amaranth oil decreased total and “bad” LDL cholesterol by 15% and 22%, respectively. Current therapy. Clini, Blumberg, R.S. Linoleic acid on the other hand is a PUFA (polyunsaturated fatty acids). ; Bousvaros, A. A significant concentration of phenolic compounds present in the acai berry leach into the oil, like vanillic acid. African Journal of Pharmacy and Pharmacology. In this study, DAI was, Loss of body weight was calculated as the difference, ght. There was no remarkable difference between the damage score of TXYF group and SASP group (q = 3.75, P>0.05). ; Crispin, D.A. Mice treated with DSS showed remarkable clinical signs, including weight loss, and reduced colon length. Treatment of, Jeong, H.J. Ferulic Acid Stabilizes a Solution of Vitamins C and E and Doubles its Photoprotection of Skin. This paper focuses on several natural occurring phenolic acids (caffeic, carnosic, ferulic, gallic, p-coumaric, rosmarinic, vanillic) and first gives an overview of their most common natural plant sources. Acai oil today could be obtained either from the wild varieties of Acai palm. The population of intestinal microflora, Bacteroides distasonis and Clostridium spp., increased significantly in mice with acute and chronic ulcerative colitis. J.F. disease: the role of environmental factors. As a buyer, it is important to note the kind of berries from which acai oil is produced. Oats are one of the world's healthiest and most nutritious foods. It’s also rich in magnesium, an essential nutrient involved in nearly 300 reactions in the body, including DNA synthesis and muscle contraction (4). The hematological parameters of the satellite group increased and the serum sodium level decreased after the treatment. On days 15 and 29, blood was collected to evaluate essential biochemical and hematological parameters. ; Gokhale, R.; Cho, J.H. Other naturally gluten-free grains include sorghum, quinoa, millet, oats, buckwheat and brown rice. detection system (Amersham Corp. Newark, NJ, least 3 experiments. The inhibition was varied with species and was dependent on concentrations. Lesage-Meessen, L.; Delattre, M.; Haon, M.; Thibault. in various amounts. ted with the antibodies. These berries, which are naturally found in the floodplains of the mighty Amazon and its numerous tributaries, were relatively unknown outside of the primitive Amazonian tribes. Amaranth is a group of more than 60 different species of grains that have been cultivated for about 8,000 years. ; Smits, R.; Xia, B.; Kuipers, E.J. It has an impressive nutrient profile and been associated with a number of impressive health benefits. Eating oats and oatmeal has many benefits for weight loss and optimal health. Summary Amaranth is high in several antioxidants, such as gallic acid, p-hydroxybenzoic acid and vanillic acid, which may help protect against disease. [4]. This article reviews whether mayo is safe when…. This method of scoring has been, mmediately centrifuged at 3,000 rpm for 15 min to, L of the sample or the IL-6 standards were added and, shing the wells, avidin-peroxidase was added, and, croplate ELISA reader. Melanin is the pigment that affects hair, skin, and eye color. Addition of CPS significantly improved the over run (%) and decrease the viable of lactic acid bacteria of carrot frozen yoghurt. When the hair is already damp, it seals the moisture, keeping them from turning dry. It is also important to note its physical properties. One review reported that amaranth is especially high in phenolic acids, which are plant compounds that act as antioxidants. ; Middleton, S.J. Satellite groups showed no other major change in biochemical parameters when compared to the control group. ; Strober W. Anim, al models of mucosal inflammation and their, Ullman, T.; Croog, V.; Harpaz, N.; Sachar, D.; It, zkowitz, S. Progression of flat low-grade, Li, Y.; de Haar, C.; Chen, M.; Deuring, J.; Gerrits, M.M. To cook amaranth, combine water with amaranth in a 3:1 ratio. ; van, Agoff, S.N. Chiang, L.C. Journal of Investigative Dermatology. Best acai oil is one that is extracted from cold pressing the flesh (and not the shell) without using any chemicals (like hexane of carbon tetrachloride) to enhance efficiency of oil recovery. day treatment with 5% DSS dissolved in the, riment, blood samples were collected from all, 2 was significantly increased in the colon tissues of DSS-treated, Effect of vanillic acid on the levels of COX-2, ced in mice by 7-day treatment with 5% DSS, s administered orally at doses of 200 mg/kg, Mice treated with sulfasalazine (150 mg/kg), clinical signs (weight loss, diarrhea, and rectal, ith vanillic acid than in those not treated with, e activated to release a host of inflammatory, elevated in UC patients [7,8].